Wolf 10

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TB-500 (Thymosin Beta-4)

Research-use-only peptide studied for cytoskeletal signaling, cell motility, and matrix remodeling in tissue-function models.

  • Assesses tissue remodeling pathways.
  • Explores angiogenic signaling models.
  • ≥99% Pure | 5X Tested | PhD-Formulated | GMP/ISO

Description

TB-500 (Thymosin Beta-4) | Product Description

TB-500 (Thymosin Beta-4) | Introduction

TB-500 refers to research-grade thymosin β4 (timbetasin), used in RUO models to probe cytoskeletal signaling, motility, and matrix remodeling. Typical readouts include actin dynamics, focal-adhesion markers, and migration/closure assays. Not intended for diagnostic or therapeutic use.

  • Actin-binding/cytoskeletal signaling
  • Cell migration & wound-closure models
  • Matrix deposition and remodeling markers
NameTB-500 (Thymosin Beta-4; Thymosin β4 Acetate)
SynonymsThymosin β4; Timbetasin; Tβ4; TB-500
SequenceAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular FormulaC212H350N56O78S
Molecular Weight~4963.5 g/mol
CAS Number77591-33-4
AppearanceWhite to off-white lyophilized powder
SolubilitySoluble in sterile or bacteriostatic water
Purity≥99% (HPLC), lot-specific
Storage Guidelines• Lyophilized: ≤0°F (–18°C), dry, protected from light/moisture
• Reconstituted: 36–46°F (2–8°C); short-term only
• Long-Term: Store dry at ≤−20°C; avoid freeze–thaw
  • Purity & Identity: ≥99% | HPLC & MS validated
  • Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
  • Stability & Process: Controlled-nucleation lyophilization | Stability-focused procedures
  • Formulation & QA: PhD-formulated | GMP / ISO-aligned manufacturing
  • Packaging: Luxe Fridge-Ready Box

Tissue-remodeling peptides are used in RUO systems to study how cells organize cytoskeleton and matrix—migration, adhesion, and protein-network balance. These models help profile dynamic protein function under strain, injury, or growth conditions.

Exciting Areas of Study

  • Actin turnover, lamellipodia/filopodia dynamics
  • ECM production and deposition assays
  • Motility, closure, and invasion models
  • Cytoskeletal signaling cross-talk (FAK, Rho/ROCK)

Research Applications

  • Quantify migration/closure kinetics in vitro
  • Probe protein–matrix signaling balance
  • Benchmark remodeling signatures vs. controls
  • Map actin-binding effects on cytoskeletal architecture
  • Evaluate matrix remodeling and adhesion markers
  • Compare motility phenotypes across stressors

This product is intended solely for laboratory research purposes. It is not suitable for human, animal, or household use. Researchers must follow institutional safety protocols. See our Terms & Conditions and our Research Compliance Disclaimers for details.

Additional information

Select Strength (MG)

10MG

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Third Party Testing

Lot number Analysis date Testing Certificate
LBL-1125-5AM-1056 February 9, 2026 Purity & Net Peptide Testing View PDF
LBL-0326-10AM-0014 March 27, 2026 Purity & Net Peptide Testing View PDF
LBL-0326-5AM5-0006 May 18, 2026 Purity & Net Peptide Testing View PDF